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500ug
| 产品编号 | bs-7579P |
| 英文名称 | TXNDC5 Antibody Blocking Peptide |
| 中文名称 | 硫氧还蛋白5封闭多肽 |
| 英文别名 | EndoPDI; Endoplasmic reticulum protein ERp46; Endothelial protein disulphide isomerase; ERP46; Hcc 2; PDIA15; Protein disulfide isomerase family A member 15; Thioredoxin domain containing 5 (endoplasmic reticulum); thioredoxin domain containing 5; Thioredoxin domain containing protein 5; Thioredoxin like protein p46; Thioredoxin related protein; Thioredoxin-like protein p46; TLP46; TXN5; TXNDC 5; UNQ364; TXND5_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Signal Transduction > Protein Trafficking > ER Proteins |
| 亚细胞定位 | Endoplasmic reticulum lumen |
| 相似性 | Belongs to the protein disulfide isomerase family. Contains 3 thioredoxin domains. |
| 功能 | Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details. |
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TXNDC5 Antibody Blocking Peptide(bs-7579P)-500ug
¥880







