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- Bioss
- bs-8729P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-8729P |
| 英文名称 | TPH2 Antibody Blocking Peptide |
| 中文名称 | 5色氨酸羟化酶2封闭多肽 |
| 英文别名 | ADHD7; Neuronal tryptophan hydroxylase; NTPH; TPH 2; Tph2; TPH2_HUMAN; Tryptophan 5-hydroxylase 2; Tryptophan 5-monooxygenase 2; Tryptophan hydroxylase 2. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmitter > Biogenic Amines > Serotonin / 5HT |
| 组织特异性 | Brain specific. |
| 相似性 | Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Contains 1 ACT domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH) and tryptophan hydroxylase 2 (TPH2) comprise a small family of monooxygenases that catalyze the rate-limiting step in the catabolism of aromatic L-amino acids and utilize tetrahydropterine as a cofactor. TPH2 is highly expressed in the central nervous system (CNS), mainly in the brain. TPH2 catalyzes the first step in the biosynthesis of serotonin in the CNS and melatonin in the pineal gland, and may be involved in the pathology of several neuropsychiatric disorders. Glucocorticoid-mediated reduction of TPH2 is associated with the etiology of mood disorders, specifically psychotic major depression, and TPH2 may be related to dysregulation of serotonin neurotransmission in the brain which commonly leads to suicidal behavior. |
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TPH2 Antibody Blocking Peptide(bs-8729P)-500ug
￥880
