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- 规格:
500ug
| 产品编号 | bs-8721P |
| 英文名称 | SEH1L Antibody Blocking Peptide |
| 中文名称 | 核通道蛋白SEH1L封闭多肽 |
| 英文别名 | Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromosome Structure > Centromeres Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Nuclear Pore Complex Signal Transduction > Protein Trafficking > Nuclear Import / Export |
| 亚细胞定位 | Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex. |
| 相似性 | Belongs to the WD repeat SEC13 family. Contains 6 WD repeats. |
| 功能 | Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats. |
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SEH1L Antibody Blocking Peptide(bs-8721P)-500ug
¥880







