SEH1L Antibody Blocking Peptide(bs-8721P)-500ug

SEH1L Antibody Blocking Peptid

e(bs-8721P)-500ug
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  • bs-8721P
  • 2025年10月16日
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      500ug

    产品编号bs-8721P
    英文名称SEH1L Antibody Blocking Peptide
    中文名称核通道蛋白SEH1L封闭多肽
    英文别名Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromosome Structure > Centromeres

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Nuclear Pore Complex

    Signal Transduction > Protein Trafficking > Nuclear Import / Export

    亚细胞定位Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex.
    相似性Belongs to the WD repeat SEC13 family.
    Contains 6 WD repeats.
    功能Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats.

     

     

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