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- Bioss
- bs-7556P
- 2025年10月16日
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500ug
| 产品编号 | bs-7556P |
| 英文名称 | ALOX5AP Antibody Blocking Peptide |
| 中文名称 | 5脂氧合酶激活蛋白封闭多肽 |
| 英文别名 | 5-lipoxygenase activating protein; Arachidonate 5 lipoxygenase activating protein; 5-lipoxygenase activating protein; AL5AP_HUMAN; ALOX 5AP; ALOX5 AP; Arachidonate 5-lipoxygenase-activating protein; Five lipoxygenase activating protein; FLAP; MK 886 binding protein; MK-886-binding protein. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators Immunology > Immune System Diseases > Allergens Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Second Messenger > Lipid Messengers |
| 亚基 | Homotrimer. Interacts with LTC4S and ALOX5. |
| 亚细胞定位 | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the MAPEG family. |
| 功能 | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.Involvement in disease: Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) ; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. |
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ALOX5AP Antibody Blocking Peptide(bs-7556P)-500ug
￥880
