GJC3 Antibody Blocking Peptide(bs-8697P)-500ug

GJC3 Antibody Blocking Peptide

(bs-8697P)-500ug
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  • bs-8697P
  • 2025年10月16日
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      500ug

    产品编号bs-8697P
    英文名称GJC3 Antibody Blocking Peptide
    中文名称间隙连接蛋白29封闭多肽
    英文别名Connexin 29; connexin29; connexin-29; Connexin 30.2; Connexin 31.3; Connexin-30.2; Connexin-31.3; CX23; Cx29 ; Cx30.2; Cx31.3; CXG3_HUMAN; Gap junction epsilon 1 protein; Gap junction epsilon-1 protein ; Gap junction gamma 3 protein; Gap junction gamma-3 protein; Gap junction protein epsilon 1 29kDa; Gap junction protein epsilon 1; Gap junction protein gamma 3 30.2kDa; Gap junction protein gamma 3; GJC 3 antibodyGJC3; GJE 1.
    纯化方法HPLC
    亚基A connexon is composed of a hexamer of connexins
    亚细胞定位Cell membrane. Cell junction, gap junction.
    组织特异性CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.
    相似性Belongs to the connexin family. Gamma-type subfamily.
    功能One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neiGHBoring cell.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Connexin 29 belongs to the connexin family and is a member of the epsilon-type subfamily. Connexin 29 is a membrane bound, multi-pass protein also known as gap junction epsilon-1 protein. A connexon, consisting of connexin hexamers, is a membrane bound structure that is integral in the formation of a gap junction. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neiGHBoring cell. Connexin 29 expression is restricted to the central nervous system and is present in brain, spinal cord, and sciatic nerve samples. It has been suggested that connexin 29 in the mature CNS contributes minimally to gap junctional intercellular communication in oligodendrocyte cell bodies. Rather, connexin 29 is targeted to myelin where it, along with connexin 32, may contribute to connexin-mediated communication between adjacent layers of uncompacted myelin.

     

     

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