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500ug
| 产品编号 | bs-8697P |
| 英文名称 | GJC3 Antibody Blocking Peptide |
| 中文名称 | 间隙连接蛋白29封闭多肽 |
| 英文别名 | Connexin 29; connexin29; connexin-29; Connexin 30.2; Connexin 31.3; Connexin-30.2; Connexin-31.3; CX23; Cx29 ; Cx30.2; Cx31.3; CXG3_HUMAN; Gap junction epsilon 1 protein; Gap junction epsilon-1 protein ; Gap junction gamma 3 protein; Gap junction gamma-3 protein; Gap junction protein epsilon 1 29kDa; Gap junction protein epsilon 1; Gap junction protein gamma 3 30.2kDa; Gap junction protein gamma 3; GJC 3 antibodyGJC3; GJE 1. |
| 纯化方法 | HPLC |
| 亚基 | A connexon is composed of a hexamer of connexins |
| 亚细胞定位 | Cell membrane. Cell junction, gap junction. |
| 组织特异性 | CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney. |
| 相似性 | Belongs to the connexin family. Gamma-type subfamily. |
| 功能 | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neiGHBoring cell. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Connexin 29 belongs to the connexin family and is a member of the epsilon-type subfamily. Connexin 29 is a membrane bound, multi-pass protein also known as gap junction epsilon-1 protein. A connexon, consisting of connexin hexamers, is a membrane bound structure that is integral in the formation of a gap junction. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neiGHBoring cell. Connexin 29 expression is restricted to the central nervous system and is present in brain, spinal cord, and sciatic nerve samples. It has been suggested that connexin 29 in the mature CNS contributes minimally to gap junctional intercellular communication in oligodendrocyte cell bodies. Rather, connexin 29 is targeted to myelin where it, along with connexin 32, may contribute to connexin-mediated communication between adjacent layers of uncompacted myelin. |
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GJC3 Antibody Blocking Peptide(bs-8697P)-500ug
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