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- Bioss
- bs-20063P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-20063P |
| 英文名称 | HTRA1 Antibody Blocking Peptide |
| 中文名称 | 丝氨酸蛋白酶11封闭多肽 |
| 英文别名 | HtrA 1; High-temperature requirement A serine peptidase 1; HtrA serine peptidase 1; HTRA1_HUMAN; L56; protease serine 11; PRSS11; Serine protease 11; Serine protease HTRA1; Serine protease HTRA1 precursor. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like |
| 亚基 | Forms homotrimers. In the presence of substrate, may form higher-order multimers in a PDZ-independent manner. Interacts with TGF-beta family members, including BMP4, TGFB1, TGFB2, activin A and GDF5. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in a variety of tissues, with strongest expression in placenta. |
| 相似性 | Belongs to the peptidase S1B family. Contains 1 IGFBP N-terminal domain. Contains 1 Kazal-like domain. Contains 1 PDZ (DHR) domain. |
| 功能 | Protease that regulate the availability of nsulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Represses signaling by TGF-beta family members. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008] |
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HTRA1 Antibody Blocking Peptide(bs-20063P)-500ug
￥880
