AMIGO3 Antibody Blocking Peptide(bs-7959P)-500ug

AMIGO3 Antibody Blocking Pepti

de(bs-7959P)-500ug
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  • bs-7959P
  • 2025年10月16日
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      500ug

    产品编号bs-7959P
    英文名称AMIGO3 Antibody Blocking Peptide
    中文名称粘附分子IgG样结构域蛋白3封闭多肽
    英文别名Adhesion molecule with Ig like domain 3; ALI3; Alivin 3; AMIGO 3; Amphoterin induced gene and ORF 3; Amphoterin induced protein 3 precursor.AMGO3_HUMAN
    纯化方法HPLC
    亚基Binds AMIGO1 or AMIGO2 (By similarity).
    亚细胞定位Membrane; Single-pass type I membrane protein
    相似性Belongs to the immunoglobulin superfamily. AMIGO family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 6 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
    功能AMIGO3 may mediate heterophilic cell-cell interaction and may also contribute to signal transduction through its intracellular domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction.

     

     

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