- ￥880
- Bioss
- bs-16625P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16625P |
| 英文名称 | IMPACT Antibody Blocking Peptide |
| 中文名称 | IMPACT蛋白封闭多肽 |
| 英文别名 | IMPACT; Impact homolog (mouse); Impact homolog; impact RWD domain protein; IMPCT_HUMAN; Imprinted and ancient gene protein homolog; MGC33718; Protein IMPACT; RWD domain containing 5; RWDD5. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Regulation |
| 亚基 | Interacts with GCN1/GCN1L1 (By similarity). |
| 亚细胞定位 | Cytoplasm (By similarity). Note=May be associated with polysomes (By similarity). |
| 组织特异性 | Widely expressed. Expressed at high level in brain. |
| 相似性 | Belongs to the IMPACT family. Contains 1 RWD domain. |
| 功能 | Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. |
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IMPACT Antibody Blocking Peptide(bs-16625P)-500ug
￥880
