- ￥880
- Bioss
- bs-11208P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11208P |
| 英文名称 | SOX4 Antibody Blocking Peptide |
| 中文名称 | 核转录因子SOX4封闭多肽 |
| 英文别名 | SOX4; SOX 4; SOX-4; Ecotropic viral integration site 16; EVI 16; EVI16; SRY (sex determining region Y) box 4; SRY box containing gene 4; SRY related HMG box gene 4; SOX4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Epigenetics and Nuclear Signaling > Transcription > Domain Families > HMG Box Neuroscience > Cell Type Marker > Neural Stem Cell marker Neuroscience > Neurology process > Neural Signal Transduction Stem Cells > Neural Stem Cells > Intracellular |
| 亚基 | Interacts with UBE2I. |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Testis, brain, and heart. |
| 相似性 | Contains 1 HMG box DNA-binding domain. |
| 功能 | The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate. SOX4 shows a high degree of sequence homology with SOX11. Both are expressed in the CNS. SOX4 and SOX11 expression increase together in the developing CNS (with some exceptions: external granule layer of the cerebellum). SOX4 knock-out mice have been shown to die of a heart defect half way through gestation with no observable CNS phenotype, although it has been proposed that SOX11 compensates for the absence of SOX4. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. |
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SOX4 Antibody Blocking Peptide(bs-11208P)-500ug
￥880
