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- bs-11203P
- 2025年10月16日
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500ug
| 产品编号 | bs-11203P |
| 英文名称 | POU3F1 Antibody Blocking Peptide |
| 中文名称 | 八聚体结合转录因子6封闭多肽 |
| 英文别名 | transcription factor 1; OCT 6; OCT 6; OCT-6; OCT-6; OCT6; OCT6; Octamer-binding protein 6; Octamer-binding transcription factor 6; OTF-6; OTF6; OTF6; PO3F1_HUMAN; POU class 3 homeobox 1; POU domain; POU domain class 3 transcription factor 1; POU domain class 3 transcription factor 1; POU domain transcription factor SCIP; POU-domain transcription factor SCIP; POU3F1; POU3F1; scip (gene name); SCIP. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > OCT Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > POU Neuroscience > Cell Type Marker > Neural Stem Cell marker Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Membrane; Multi-pass membrane protein (Potential). Cell membrane. Note=Detected in the plasma mebrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. |
| 组织特异性 | Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in hematopoietic cells, including CD34(+) leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase. |
| 相似性 | Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. |
| 功能 | High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the organic zwitterions transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]. |
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POU3F1 Antibody Blocking Peptide(bs-11203P)-500ug
￥880
