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- Bioss
- bs-11184P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11184P |
| 英文名称 | MOBP Antibody Blocking Peptide |
| 中文名称 | 少突胶质细胞髓鞘相关蛋白封闭多肽 |
| 英文别名 | MGC87379; Myelin associated oligodendrocyte basic protein; MOBP_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cytoplasm, perinuclear region. Note=Present in the major dense line of CNS myelin (By similarity). |
| 功能 | MOBP (Myelin-associated oligodendrocytic basic protein) is abundantly expressed specifically in oligodendrocytes and is the third most abundant protein in CNS myelin. MOBP is present in the major dense line of CNS myelin suggesting a role in the compaction or stabilization of myelin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The gene encoding MOBP a member of the central nervous system myelin-constituting proteins, maps to chromosome 3p22.2. MOBP has many splice variants that share a 68 amino acid N-terminal domain. MOBP-71, MOBP-81A, MOBP-99, and MOBP-169 are MOBP splice variants that contain exon 8b, which is similar to myelin basic protein (MBP) mRNA RTS, however MOBP-69, MOBP-81B, and MOBP-170 lack this exon. The splice variants that contain exon 8b are expressed in myelin, while those lacking exon 8b are retained in the oligodendrocyte soma. Exon 8b-containing variants are directed to sites of myelin sheath assembly by exon 8b, where they play a structural role in myelin formation. Splice variants lacking exon 8b likely play a cellular and/or regulatory role. MOBP is implicated in multiple sclerosis (MS), a human demyelinating disease, and in allergic encephalomyelitis in rodents. |
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MOBP Antibody Blocking Peptide(bs-11184P)-500ug
￥880
