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| 产品编号 | bs-18562P |
| 英文名称 | Macro H2A.2 Antibody Blocking Peptide |
| 中文名称 | 异型组蛋白H2A.2封闭多肽 |
| 英文别名 | Core histone macro H2A2.2; Core histone macro-H2A.2; Core histone macroH2A2.2; H2A histone family member Y2; H2AFY2; H2AW_HUMAN; Histone macroH2A2; Macro H2A2; MacroH2A.2; MacroH2A2; mH2A2. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Histones > Variants |
| 亚细胞定位 | Nucleus. Chromosome. Enriched in inactive X chromosome chromatin and in senescence-associated heterochromatin. |
| 相似性 | Contains 1 histone H2A domain. Contains 1 Macro domain. |
| 功能 | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验Purification Of Anti Peptide Antibody
peptide to the resin. Thaw serum- dilute 1:1 with TBS and filter through a 0.2 um filter Load the serum over the column, taking at least 20 minute total. Run the breakthrough over the column five times. Alternatively you can use
Purification Of Anti Peptide Antibody
Purification Of Anti Peptide Antibody Claire Walczak January 1996 Protocol: All steps up to the dialysis at rt. Pour column in TBS (=0.15M NaCl, 20mM TrisCl pH 7.4). We use a 5 ml column for 25 mls
or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
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