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500ug
| 产品编号 | bs-18562P |
| 英文名称 | Macro H2A.2 Antibody Blocking Peptide |
| 中文名称 | 异型组蛋白H2A.2封闭多肽 |
| 英文别名 | Core histone macro H2A2.2; Core histone macro-H2A.2; Core histone macroH2A2.2; H2A histone family member Y2; H2AFY2; H2AW_HUMAN; Histone macroH2A2; Macro H2A2; MacroH2A.2; MacroH2A2; mH2A2. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Histones > Variants |
| 亚细胞定位 | Nucleus. Chromosome. Enriched in inactive X chromosome chromatin and in senescence-associated heterochromatin. |
| 相似性 | Contains 1 histone H2A domain. Contains 1 Macro domain. |
| 功能 | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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Macro H2A.2 Antibody Blocking Peptide(bs-18562P)-500ug
¥880







