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- bs-23735P
- 2025年10月16日
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500ug
| 产品编号 | bs-23735P |
| 英文名称 | Fibulin 5 Antibody Blocking Peptide |
| 中文名称 | 衰老关键蛋白封闭多肽 |
| 英文别名 | ARMD3; Dance; Developmental arteries and neural crest EGF like protein; FBLN5; FIBL 5; Developmental arteries and neural crest EGF-like protein; EVEC; Fbln5; FBLN5_HUMAN; UP50; FIBL 5; FIBL-5; Fibulin-5; FLJ90059; Urine p50 protein. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Atherosclerosis > Hypertension > Vascular remodelling > Integrins Cardiovascular > Vasculature > Smooth muscle cell (SMC) > Extracellular matrix Cardiovascular > Vasculature > Vasculature Markers > Arterial Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Endothelial Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Vascular Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Beta Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Elastin |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes. |
| 相似性 | Belongs to the fibulin family. Contains 6 EGF-like domains. |
| 功能 | Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Fibulin 5: A protein that belongs to a family of extracellular proteins expressed in the basement membranes of blood vessels. Fibulin 5 may be essential for the polymerization of elastin. Missense mutations in FBLN5, the gene that encodes fibulin 5, appear responsible for 1-2% of cases of age-related macular degeneration (AMD). FBLN5 is located on chromosome 14 in band 14q32.1. See also: Fibulin 3. May play a role in vascular growth and maturation during development and in lesions of injured vessels. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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