- ￥880
- Bioss
- bs-17639P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-17639P |
| 英文名称 | SPCA2 Antibody Blocking Peptide |
| 中文名称 | ATP酶2C2封闭多肽 |
| 英文别名 | AT2C2_HUMAN; ATP2C2; ATPase 2C2; ATPase, Ca++ transporting, type 2C, member 2; Calcium-transporting ATPase type 2C member 2; DKFZp686H22230; hSPCA2; KIAA0703; PMR1; Secretory pathway Ca(2+)-ATPase 2; secretory pathway calcium ATPase 2. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Metabolism > Plasma Membrane > ATPases |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. |
| 相似性 | Belongs to the cation transport ATPase (P-type) (TC3.A.3) family. Type IIA subfamily. |
| 功能 | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The family of P-type Ca2+-transport ATPases is made up of three subfamilies: sarco(endo)plasmic-reticulum Ca2+ ATPases (SERCA), plasma- membrane Ca2+ ATPases (PMCA), and secretory-pathway Ca2+ ATPases (SPCA). The SPCA1 protein (encoded for by the ATP2C1 gene) is a Ca2+/ Mn2+-transport ATPase. It localizes to the Golgi apparatus and, together with SERCA2, it is responsible for the ionic milieu in the Golgi lumen. SPCA2 (encoded by the ATP2C2 gene) also localizes to the golgi apparatus and has a higher enzymatic turnover rate than that of SPCA1 while having a high affinity for cytosolic Ca2+. The enzymatic properties of the human SPCA2 enzyme and the restriction of its tissue expression to the gastrointestinal and respiratory tracts, prostate, thyroid, salivary, and mammary glands may, in principle ,define a Ca2+-ATPase pump with a specific physiological role in secretory cells. |
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SPCA2 Antibody Blocking Peptide(bs-17639P)-500ug
￥880
