SPATS2 Antibody Blocking Peptide(bs-17638P)-500ug

SPATS2 Antibody Blocking Pepti

de(bs-17638P)-500ug
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  • ¥880
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  • bs-17638P
  • 2025年10月16日
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      500ug

    产品编号bs-17638P
    英文名称SPATS2 Antibody Blocking Peptide
    中文名称富含丝氨酸精子发生相关蛋白2封闭多肽
    英文别名Nbla00526; p59scr; SCR59; Serine-rich spermatocytes and round spermatid 59 kDa protein; SPAS2_HUMAN; SPATA10; Spats2; Spermatogenesis-associated serine-rich protein 2.
    纯化方法HPLC
    研究领域

    Developmental Biology > Reproduction > Germ cell markers

    亚基Belongs to the SPATS2 family.
    亚细胞定位Cytoplasm.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SPATS2 is a 545 amino acid cytoplasmic protein that belongs to the SPATS2 family. The gene encoding SPATA10 maps to human chromosome 12q13.12 and mouse chromosome 15 F1. Chromosome 12 makes up about 4.5% of the human genome and is linked to a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

     

     

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