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- Bioss
- bs-15093P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15093P |
| 英文名称 | C20orf134 Antibody Blocking Peptide |
| 中文名称 | 20号染色体开放阅读框134封闭多肽 |
| 英文别名 | C20orf134; CT134_HUMAN; Putative uncharacterized actin family protein C20orf134. |
| 纯化方法 | HPLC |
| 亚基 | Associates with the U5 snRNP particle. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, NHP2L1, EFTUD2, SART1 and USP39, LSm proteins LSm2-8 and Sm proteins. Interacts with ARAF1. Identified in the spliceosome C complex. Interacts with AR and NR3C1, but not ESR1, independently of the presence of hormones. |
| 亚细胞定位 | Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles. |
| 组织特异性 | Widely expressed. |
| 相似性 | Belongs to the actin family. |
| 功能 | Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C20orf134 is a 245 amino acid secreted protein that belongs to the Actin family and is encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception. |
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C20orf134 Antibody Blocking Peptide(bs-15093P)-500ug
￥880
