- ￥880
- Bioss
- bs-12514P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12514P |
| 英文名称 | ARFRP1 Antibody Blocking Peptide |
| 中文名称 | ADP核糖基化因子相关蛋白1 |
| 英文别名 | ADP ribosylation factor related protein 1; ARF related protein 1; ARF related protein; ARL 18; ARL18; ARP 1; ARP; ARP1; Helicase like protein NHL; MGC6837; SCG10 like protein; ARFRP_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Golgi Proteins |
| 亚基 | Interacts with SYS1. |
| 亚细胞定位 | Golgi Apparatus |
| 组织特异性 | Found in most tissues. |
| 相似性 | Belongs to the small GTPase superfamily. Arf family. |
| 功能 | ARFRP1 (ARF related protein 1) is a membrane-associated GTP-ase and localizes to the plasma membrane. It is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. ARFPR1 is possibly involved in plasma membrane related signaling events. ARFRP1 interacts with SYS1 and is located in Golgi and found in most tissues. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis. |
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ARFRP1 Antibody Blocking Peptide(bs-12514P)-500ug
￥880
