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- 详细信息
- 技术资料
- 规格:
500ug
| 产品编号 | bs-16564P |
| 英文名称 | TRAFD1 Antibody Blocking Peptide |
| 中文名称 | TRAFD1蛋白封闭多肽 |
| 英文别名 | FLN29; FLN29 gene product; Protein FLN29; TRAD1_HUMAN; TRAF type zinc finger domain containing 1; TRAF type zinc finger domain containing protein 1; TRAF-type zinc finger domain-containing protein 1; TRAFD 1. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > TLR Signaling |
| 相似性 | Contains 1 TRAF-type zinc finger. |
| 功能 | Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009] |
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TRAFD1 Antibody Blocking Peptide(bs-16564P)-500ug
¥880





