- ￥880
- Bioss
- bs-16562P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16562P |
| 英文名称 | TRAF4AF1 Antibody Blocking Peptide |
| 中文名称 | TRAF4相关因子1封闭多肽 |
| 英文别名 | KNSTRN; C15orf23; chromosome 15 open reading frame 23; HSD11; Kinastrin; Kinetochore-localized astrin-binding protein; Kinetochore-localized astrin/SPAG5-binding protein; Putative TRAF4-associated factor 1; SKAP; small kinetochore associated protein; T4AF1_HUMAN; TRAF4 associated factor 1; TRAF4-associated factor 1; Traf4af1. |
| 纯化方法 | HPLC |
| 亚基 | Part of an astrin (SPAG5)-kinastrin (SKAP) complex containing KNSTRN, SPAG5, PLK1, DYNLL1 and SGOL2. Interacts with SPAG5. Directly binds to microtubules, although at relatively low affinity. Interacts with CENPE; this interaction greatly favors microtubule-binding. |
| 亚细胞定位 | Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole. Note=Colocalizes with microtubules around centrosomes in prophase and with the mitotic spindle at prometaphase and metaphase. From late prometaphase to anaphase, is highly concentrated on kinetochores. Located at the kinetochore-microtubule interface. The astrin (SPAG5)-kinastrin (SKAP) complex localizes to the microtubule plus ends. |
| 功能 | Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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TRAF4AF1 Antibody Blocking Peptide(bs-16562P)-500ug
￥880
