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500ug
| 产品编号 | bs-12482P |
| 英文名称 | phospho-ANAPC1 (Ser688) Antibody Blocking Peptide |
| 中文名称 | 磷酸化细胞周期末期促进复合蛋白APC1封闭多肽 |
| 英文别名 | phospho-ANAPC1(Ser688); Apc1 (phospho S688); ANAPC 1; ANAPC1; Anaphase promoting complex subunit 1; anaphase-promoting complex 1 (meiotic checkpoint regulator); Anaphase-promoting complex subunit 1; Apc 1; APC1; APC1_HUMAN; Cyclosome subunit 1; MCPR; Meiotic checkpoint regulator; Mitotic checkpoint regulator; Protein Tsg 24; Protein Tsg24; Testis-specific gene 24 protein; TSG 24; TSG24. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > APC/C |
| 亚基 | The APC/C is composed of at least 12 subunits. |
| 翻译后修饰 | Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis. |
| 相似性 | Belongs to the APC1 family. Contains 4 PC repeats. |
| 功能 | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]. |
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phospho-ANAPC1 (Ser688) Antibody Blocking Peptide(bs-12482P)-500ug
¥1080







