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- Bioss
- bs-2183P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2183P |
| 英文名称 | CLDN11 Antibody Blocking Peptide |
| 中文名称 | 少突胶质细胞跨膜蛋白封闭多肽 |
| 英文别名 | Oligodendrocyte Specific Protein; Oligodendrocyte transmembrane protein; Claudin 11; claudin11; claudin-11; CLDN 11; CLDN11; Oligodendrocyte transmembrane protein; OSP; OTM. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Immune System Diseases > Autoimmune Neuroscience > Cell Type Marker > Glia marker > Oligodendrocyte marker Neuroscience > Neurology process > Neurodegenerative disease |
| 亚基 | Interacts with tetraspanin-3/TSPAN3. |
| 亚细胞定位 | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the claudin family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Oligodendrocyte specific protein (OSP)is the third most abundant component of central nervous system myelin. The claudin superfamily consists of many structurally related proteins. These proteins, which include claudin 1 through 18, are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that OSP/Claudin 11 determines the permeability between layers of myelin sheaths via focal adhesion. Its expression is highly regulated during development, suggesting that it may play an important role in the growth and differentiation of oligodendrocytes and other cells outside the CNS. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease. |
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CLDN11 Antibody Blocking Peptide(bs-2183P)-500ug
￥880
