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- bs-0446P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-0446P |
| 英文名称 | FOXE1 Antibody Blocking Peptide |
| 中文名称 | 甲状腺转录因子-2封闭多肽 |
| 英文别名 | FKH L15; FKHL 15; FKHL15; Forkhead (Drosophila) like 15; forkhead (Drosophila)-like 15; forkhead box E1; Forkhead box E2; Forkhead box protein E1; Forkhead drosophila homolog like 15; Forkhead like 15; Forkhead related protein FKHL 15; Forkhead related protein FKHL15; FOX E1; FOX E2; FOXE 1; FOXE 2; FOXE-2; FOXE1; FOXE2; HFKH 4; HFKH4; HFKL 5; HFKL5; homolog-like 15; thyroid transcription factor 2; thyroid transcription factor-2; TITF 2; TITF2; TTF 2; TTF-2; TTF2; FOXE1_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus (Potential). |
| 组织特异性 | Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas. |
| 翻译后修饰 | Phosphorylated. |
| 相似性 | Contains 1 fork-head DNA-binding domain. |
| 功能 | Probable transcription factor. Could be involved in thyroid gland organogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Thyroid transcription factor 2 (TITF2; Forkhead; TH; also known as a "winged helix") . FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as monomers, are also found in the Hepatocyte nuclear factor (HNF) proteins, which provide tissue-specific gene regulation. The structure contains 2 flexible loops or "wings" in the C-terminal region, hence the term winged helix. Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. TISSUE SPECIFICITY: Thyroid and lung. subcellular location: Nucleus Belongs to the NK-2 homeobox family. |
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FOXE1 Antibody Blocking Peptide(bs-0446P)-500ug
￥880
