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TRAPPC4 Antibody Blocking Pept

ide(bs-16585P)-500ug
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  • 2025年10月16日
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      500ug

    产品编号bs-16585P
    英文名称TRAPPC4 Antibody Blocking Peptide
    中文名称SBDN蛋白封闭多肽
    英文别名CGI 104; Hematopoietic stem/progenitor cell protein 172; HSPC172; PTD009; SBDN; TPPC4_HUMAN; Synbindin; Trafficking protein particle complex subunit 4; TRAPPC4; TRS23; TRS23 homolog.
    纯化方法HPLC
    亚基Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Interacts with SDC2 (By similarity).
    亚细胞定位Endoplasmic reticulum and Golgi Apparatus
    相似性Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity).
    Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.
    功能TRAPPC4 is part of the multisubunit TRAPP (transport protein particle) complex and interacts with SDC2. It may play a role in vesicular transport from endoplasmic reticulum to Golgi. TRAPP proteins are involved in tethering during vesicle transport.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料TRAPPC4 is a postsynaptic protein belonging to the TRAPPC4 subfamily of the TRAPP small subunits family of proteins. Expressed in neurons and localizing to the Golgi apparatus, TRAPPC4 is believed to be involved in vesicular transport from the endoplasmic reticulum (ER) to the Golgi, functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Similar to other proteins involved in vesicular transport or synaptic function, TRAPPC4 contains a nonclassical PDZ domain, a TRAPPC1-like domain and a C-terminus that is similar to a short segment of RyR. Via its nonclassical PDZ domain, TRAPPC4 binds to the C-terminal EFYA motif of Syndecan-2, suggesting that TRAPPC4 may play an important role in dendritic spine morphogenesis through membrane-trafficking.

     

     

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