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500ug
| 产品编号 | bs-0664P |
| 英文名称 | HMGB1 Antibody Blocking Peptide |
| 中文名称 | 高迁移率族蛋白B1封闭多肽 |
| 英文别名 | Amphoterin; High mobility group 1; High Mobility Group Box 1; High mobility group protein 1; High mobility group protein B1; HMG3; HMGB 1;HMGB-1; Hmgb1 protein; Nonhistone chromosomal protein HMG1; SBP 1; SBP-1; Sulfoglucuronyl carbohydrate binding protein; HMGB1_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Histones > HMGs Epigenetics and Nuclear Signaling > Transcription > Domain Families > HMG Box Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Signal Transduction > Antibodies > hmgb1 |
| 亚基 | Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. |
| 亚细胞定位 | Nucleus. Chromosome. |
| 相似性 | Belongs to the HMGB family.
Contains 2 HMG box DNA-binding domains. |
| 功能 | DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models |
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HMGB1 Antibody Blocking Peptide(bs-0664P)-500ug
¥880







