CLDN10 Antibody Blocking Peptide(bs-13739P)-500ug

CLDN10 Antibody Blocking Pepti

de(bs-13739P)-500ug
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  • ¥880
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  • bs-13739P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-13739P
    英文名称CLDN10 Antibody Blocking Peptide
    中文名称紧密连接蛋白10封闭多肽
    英文别名Claudin-10; Claudin10; CLD10_HUMAN; CLDN 10; CLDN10; CLDN10 protein; CPETRL 3; CPETRL3; HGNC:2033; OSP L; OSP like protein; OSP-like protein; OSPL.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Endothelial

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Gap Junctions

    亚细胞定位Cell junction, tight junction. Cell membrane.
    相似性Belongs to the claudin family.
    功能Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-10 is a 228 amino acid multi-pass membrane protein that belongs to the claudin family and plays an important role in cell-adhesion activity and tight junction-specific events.

     

     

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