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- 规格:
500ug
| 产品编号 | bs-0075P |
| 英文名称 | PNOC Antibody Blocking Peptide |
| 中文名称 | 孤菲肽/痛敏肽封闭多肽 |
| 英文别名 | PNOC; N/OFQ; N23K; N23K/N27K; Nociceptin, included; Npnc1; OFQ; OFQ/N; Orphanin FQ; PPNOC; prepronociceptin; Propronociceptin; PNOC_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmitter > Neuropeptides > Opioids Neuroscience > Sensory System > Somatosensory system > Nociception |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Predominantly in the brain and spinal cord. |
| 相似性 | Belongs to the opioid neuropeptide precursor family. |
| 功能 | Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Nociceptin/orphanin FQ (N/OFQ), a 17-amino acid neuropeptide, is the endogenous ligand for the nociceptin receptor (NOP, ORL-1), and initiates its function to act on numerous brain activities such as pain sensation and fear learning. It is derived from the prepronociceptin protein, as are a further 2 peptides, nocistatin & NocII, which inhibit the N/OFQ receptor function. Nociceptin itself acts as a potent anti-analgesic, effectively counteracting the effect of pain-relievers. The gene coding for prepronociceptin is located on Ch8p21 in humans. Nociceptin acts at the Nociceptin receptor (NOP receptor) formerly known as ORL1. |
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PNOC Antibody Blocking Peptide(bs-0075P)-500ug
¥880







