- ￥880
- Bioss
- bs-16558P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16558P |
| 英文名称 | HSF5 Antibody Blocking Peptide |
| 中文名称 | 热休克因子蛋白5封闭多肽 |
| 英文别名 | FLJ40311; Heat shock factor protein 5; Heat shock transcription factor 5; Heat shock transcription factor family member 5; HSF 5; HSF5; HSF5_HUMAN; HSTF 5; MGC134827. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the HSF family. |
| 功能 | May act as a transcriptional factor. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HSF5 is a 596 amino acid protein that localizes to the nucleus and is thought to function as a transcription factor. Multiple isoforms of HSF5 exist due to alternative splicing events. The gene encoding HSF5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
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HSF5 Antibody Blocking Peptide(bs-16558P)-500ug
￥880
