PCDHB2 Antibody Blocking Peptide(bs-11136P)-500ug

PCDHB2 Antibody Blocking Pepti

de(bs-11136P)-500ug
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  • bs-11136P
  • 2025年10月16日
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      500ug

    产品编号bs-11136P
    英文名称PCDHB2 Antibody Blocking Peptide
    中文名称原钙粘蛋白β2封闭多肽
    英文别名MGC111392; PCDH beta 2; PCDH beta2; PCDHB 2; Protocadherin beta 2; PCDB2_HUMAN.
    纯化方法HPLC
    亚细胞定位Cell membrane; Single-pass type I membrane protein.
    相似性Contains 6 cadherin domains.
    功能PCDHB2 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. It is a potential neural cadherin-like calcium-dependent cell-adhesion protein and may be involved in the establishment and maintenance of specific neuronal connections in the brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes.PCDHB2 (protocadherin beta 2), whose alternative names include MGC111392 or PCDH-BETA2, is one of 16 proteins in the protocadherin beta cluster, and contains 798 amino acids. PCDHB2 is a single-pass type I membrane protein which is involved in maintaining specific neuronal connections in the brain. PCDHB2 contains six cadherin domains and has a potential role in calcium-dependent cell-adhesion.Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB2) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein.

     

     

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