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500ug
| 产品编号 | bs-12438P |
| 英文名称 | LRRFIP2 Antibody Blocking Peptide |
| 中文名称 | LRRFIP2蛋白封闭多肽 |
| 英文别名 | 5133400F20Rik; AI850587; DKFZp434H2035; FLJ20248; FLJ22683; FLJ58304; HUFI 2; Leucine rich repeat (in FLII) interacting protein 2; Leucine rich repeat flightless interacting protein 2; Leucine-rich repeat flightless-interacting protein 2; LRR FLII interacting protein 2; LRR FLII-interacting protein 2; LRRF2_HUMAN; Lrrfip2. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > NFkB pathway Immunology > Innate Immunity > Macrophage / Inflamm. Immunology > Innate Immunity > TLR Signaling Signal Transduction > Signaling Pathway > Nuclear Signaling > NFkB Pathway Stem Cells > Signaling Pathways > Wnt > Cytoplasmic |
| 组织特异性 | Ubiquitous with higher expression in heart and skeletal muscle. |
| 相似性 | Belongs to the LRRFIP family. |
| 功能 | May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | LRRFIP2 is a 721 amino acid protein that belongs to the LRRFIP family. Ubiquitously expressed, LRRFIP2 acts as an activator of the Wnt signaling pathway and as a positive regulator of NFⅹB activity. LRRFIP2 may be involved in regulating cytokine production in macrophages, suggesting a functional role in the TLR4-mediated inflammatory response. Three isoforms of LRRFIP2 exists due to alternative splicing events. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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