DAAM2 Antibody Blocking Peptide(bs-12430P)-500ug

DAAM2 Antibody Blocking Peptid

e(bs-12430P)-500ug
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  • ¥880
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  • bs-12430P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-12430P
    英文名称DAAM2 Antibody Blocking Peptide
    中文名称形态发生紊乱关联激活因子2封闭多肽
    英文别名DAAM2; DAAM2_HUMAN; Disheveled-associated activator of morphogenesis 2; dishevelled associated activator of morphogenesis 2; dJ90A20A.1; KIAA0381; MGC90515; RP1 278E11.1.
    纯化方法HPLC
    研究领域

    Stem Cells > Signaling Pathways > Wnt > Cytoplasmic

    组织特异性Expressed in most tissues examined.
    相似性Belongs to the formin homology family.
    Contains 1 DAD (diaphanous autoregulatory) domain.
    Contains 1 FH1 (formin homology 1) domain.
    Contains 1 FH2 (formin homology 2) domain.
    Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

     

     

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