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- Bioss
- bs-11123P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11123P |
| 英文名称 | PCDHA10 Antibody Blocking Peptide |
| 中文名称 | 钙粘蛋白相关神经受体8封闭多肽 |
| 英文别名 | Cadherin related neuronal receptor 8; CNR 8; Cnr3; CNR8; CNRN 8; CNRN-8; CNRS 8; CNRS8; CRNR 8; Crnr3; CRNR8; Ortholog to mouse CNR8; PCDH alpha10; PCDHA 10; Pcdha14; PCDHALPHA10; Protocadherin alpha 10; rCNRv10; PCDAA_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. |
| 相似性 | Contains 6 cadherin domains. |
| 功能 | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. These genes generate thousands of different protocadherin proteins through alternative promoter usage and cis-alternative splicing. PCDHA and PCDHG family members form oligomers, which also increases the diversity of PCDH proteins at the cell surface. All three gene clusters, PCDHA, PCDHB, and PCDHG show upregulated expression during brain development, and PCDHA is subsequently downregulated by myelination. Expression of all three clusters continues in the olfactory bulb, hippocampus and cerebellum until adulthood. Members of the PCDH family are potential targets in schizophrenia and bipolar disorder pathogenesis. PCDHA10 produces at least three isoforms by alternative splicing. |
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PCDHA10 Antibody Blocking Peptide(bs-11123P)-500ug
￥880
