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- Bioss
- bs-0445P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-0445P |
| 英文名称 | IL1RAPL1 Antibody Blocking Peptide |
| 中文名称 | 白介素1受体相关蛋白样1前体蛋白封闭多肽 |
| 英文别名 | IL 1 RAPL 1; IL 1RAPL 1; IL-1-RAPL-1; IL-1RAPL-1; IL1R8; IL1RAPL 1; IL1RAPL; IL1RAPL-1; IL1RAPL1; Interleukin 1 receptor 8; Interleukin 1 receptor accessory protein like 1; Interleukin-1 receptor accessory protein-like 1; IRPL1_HUMAN; Mental retardation X linked 10; Mental retardation X linked 21; Mental retardation X linked 34; MRX 21; MRX 34; MRX10; MRX21; MRX34; Oligophrenin 4; Oligophrenin-4; Oligophrenin4; OPHN 4; OPHN4; Three immunoglobulin domain containing IL 1 receptor related 2; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR 2; TIGIRR-2; TIGIRR2 antibody X linked interleukin 1 receptor accessory protein like 1; X-linked interleukin-1 receptor accessory protein-like 1. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurogenesis Neuroscience > Neurotransmission > Calcium Signaling > Calcium Channels > N-type |
| 亚细胞定位 | Cell membrane. Cytoplasm. May localize to the cell body and growth cones of dendrite-like processes. |
| 组织特异性 | Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver. |
| 相似性 | Belongs to the interleukin-1 receptor family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain. |
| 功能 | May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. |
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IL1RAPL1 Antibody Blocking Peptide(bs-0445P)-500ug
￥880
