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500ug
| 产品编号 | bs-0735P |
| 英文名称 | FGF8 Antibody Blocking Peptide |
| 中文名称 | 成纤维细胞生长因子8封闭多肽 |
| 英文别名 | AIGF; Androgen induced growth factor; Androgen-induced growth factor; FGF 8; FGF-8; FGF8; Fibroblast growth factor 8 (androgen induced); Fibroblast growth factor 8 precursor; HBGF 8; HBGF-8; HBGF8; FGF8_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > FGF Cardiovascular > Angiogenesis > Growth Factors > FGF > FGF Developmental Biology > Embryogenesis > Morphogens Developmental Biology > Lineage specification > Trophectoderm Signal Transduction > Growth Factors/Hormones > FGF Stem Cells > Mesenchymal Stem Cells > Myogenesis |
| 亚基 | Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the heparin-binding growth factors family. |
| 功能 | Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Keratinocyte growth factor precursor (KGF) (Fibroblast growth factor 8; FGF-8; HBGF-8). Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells. Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis. [Subcellular location] Secreted. [Tissue specificity] Absent in normal mammary glands and detected only in adult testis and ovary and in midgestational embryos. [Induction] By androgens. Belongs to the heparin-binding growth factors family. |
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