PCDHA3 Antibody Blocking Peptide(bs-11117P)-500ug

PCDHA3 Antibody Blocking Pepti

de(bs-11117P)-500ug
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  • ¥880
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  • bs-11117P
  • 2025年10月16日
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      500ug

    产品编号bs-11117P
    英文名称PCDHA3 Antibody Blocking Peptide
    中文名称原钙粘附蛋白α3封闭多肽
    英文别名KIAA0345 like 11; PCDH alpha 3; Protocadherin alpha 3; PCDA3_HUMAN.
    纯化方法HPLC
    亚细胞定位Cell membrane; Single pass type I membrane protein.
    相似性 Contains 6 cadherin domains.
    功能PCDHA3 contains six cadherin domains. It is thought to be a calcium dependent cell adhesion protein and may be involved in the establishment and maintenance of specific neuronal connections in the brain. There are two named isoforms.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protein products of PCDH-alpha genes interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA3 (Protocadherin alpha-3) is a 950 amino acid single-pass transmembrane protein that contains six cadherin domains. PCDHA3 is a unique cadherin in that it likely functions in spermatogenesis and may also have a role in organizing germ cell-specific structures, such as the flagellum, acrosome and intercellular bridge. There are two isoforms of PCDHA13 that are produced as a result of alternative splicing events.

     

     

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