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500ug
| 产品编号 | bs-11095P |
| 英文名称 | NEGR1 Antibody Blocking Peptide |
| 中文名称 | 神经生长调节蛋白1封闭多肽 |
| 英文别名 | A kindred of IgLON; DMML2433; IgLON family member 4; IGLON4; KILON; Neuronal growth regulator 1; Neurotractin; Ntra; PRO4993; UNQ2433; NEGR1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Organogenesis > Nervous system development Metabolism > Types of disease > Obesity Neuroscience > Cell Adhesion Proteins > Membrane Proteins Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor |
| 相似性 | Belongs to the immunoglobulin superfamily. IgLON family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NEGR1 is a 354 amino acid protein belonging to the IgLON family and immunoglobulin superfamily. NEGR1 may play a role in cell adhesion and regenerative axon sprouting in the mammalian brain and is highly expressed in adult hippocampus, cerebrum and brainstem, with much lower levels found in cerebellum. Localizing to the cell membrane at the glycosylphosphatidylinositol anchor (GPI) anchor, NEGR1 contains three Ig-like C2-type (immunoglobulin-like) domains. NEGR1 is encoded by a gene that maps to human chromosome 1p31.1, and is one of several loci associated with body mass index (BMI), possibly contributing to the development of obesity. |
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NEGR1 Antibody Blocking Peptide(bs-11095P)-500ug
¥880







