FJX1 Antibody Blocking Peptide(bs-12404P)-500ug

FJX1 Antibody Blocking Peptide

(bs-12404P)-500ug
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  • bs-12404P
  • 2025年10月16日
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      500ug

    产品编号bs-12404P
    英文名称FJX1 Antibody Blocking Peptide
    中文名称四连接同源蛋白FJX1封闭多肽
    英文别名FJX1 four jointed box 1 Drosophila; FLJ22416; FLJ25593; Four jointed box 1; Four jointed box 1 Drosophila; Four jointed protein homolog; four-jointed box protein 1; Putative secreted ligand homologous to FJX1; FJX1_HUMAN.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Neurogenesis

    Stem Cells > Signaling Pathways > Notch > Secreted

    亚细胞定位Secreted
    翻译后修饰Glycosylated (By similarity).
    Undergoes proteolytic cleavage (By similarity).
    相似性Belongs to the FJX1/FJ family.
    功能FJX1 is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. The exact function of this gene in humans is not known.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FJX1 is a 437 amino acid protein that belongs to the FJX1/FJ family. FJX1 is highly conserved in vertebrates and is expressed in the peripheral nervous system, epithelial cells of multiple organs and during limb development. FJX1 is processed and secreted as a presumptive ligand and may act as an inhibitor of dendrite extension and branching. In Drosophila, FJX1 is important for growth and differentiation of legs and wings, and for proper development of the eyes. FAT4, an essential gene that has a key role in vertebrate PCP (planar cell polarity), represses FJX1 expression which may lead to cystic diseases in humans.

     

     

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