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500ug
| 产品编号 | bs-23494P |
| 英文名称 | CD1B Antibody Blocking Peptide |
| 中文名称 | T淋巴细胞CD1B封闭多肽 |
| 英文别名 | CD1b; CD1b antigen; CD1B antigen b polypeptide; CD1b molecule; CD1B_HUMAN; Cortical thymocyte antigen CD1B ; R1; T-cell surface glycoprotein CD1b; T6/Leu6; Thymocite antigen CD1B. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > B Cells > CD Immunology > Cell Type Markers > Non-CD > APC |
| 亚细胞定位 | Cell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts. |
| 组织特异性 | Cell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts. |
| 相似性 | Contains 1 Ig-like (immunoglobulin-like) domain. |
| 功能 | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008] |
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CD1B Antibody Blocking Peptide(bs-23494P)-500ug
¥880







