procollagen type IIA/Collagen
II N-terminal propeptide Antibody Blocking Peptide(bs-11069P)-500ug- ￥880
- Bioss
- bs-11069P
- 2025年10月16日
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500ug
| 产品编号 | bs-11069P |
| 英文名称 | procollagen type IIA/Collagen II N-terminal propeptide Antibody Blocking Peptide |
| 中文名称 | Ⅱ型胶原α1 N端前体肽封闭多肽 |
| 英文别名 | Collagen II N-terminal propeptide; Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1(II); type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; COL11A3; Collagen alpha 1(II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital); MGC131516; SEDC; Collagen alpha-1(II) chain; Alpha-1 type II collagen; CO2A1_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Homotrimers of alpha 1(II) chains. |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Isoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte. |
| 翻译后修饰 | Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some of the chains.
The N-telopeptide is covalently linked to the helical COL2 region of alpha 1(IX), alpha 2(IX) and alpha 3(IX) chain. The C-telopeptide is covalently linked to an another site in the helical region of alpha 3(IX) COL2. |
| 相似性 | Belongs to the fibrillar collagen family. Contains 1 fibrillar collagen NC1 domain. Contains 1 VWFC domain. |
| 功能 | Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008] |
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procollagen type IIA/Collagen II N-terminal propeptide Antibody Blocking Peptide(bs-11069P)-500ug
￥880
