- ￥880
- Bioss
- bs-11065P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11065P |
| 英文名称 | SNTG2 Antibody Blocking Peptide |
| 中文名称 | 肌蛋白结合蛋白γ2封闭多肽 |
| 英文别名 | G2SYN; Gamma2-syntrophin; SNTG2; SYN5; Syntrophin-5; Syntrophin5; Syntrophin 5; Syntrophin gamma 2; SNTG2_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with the dystrophin protein DMD and related proteins DTNA and DTNB. |
| 亚细胞定位 | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane. |
| 组织特异性 | Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. |
| 相似性 | Belongs to the syntrophin family. Contains 1 PDZ (DHR) domain. Contains 1 PH domain. |
| 功能 | Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. |
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SNTG2 Antibody Blocking Peptide(bs-11065P)-500ug
￥880
