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- Bioss
- bs-23382P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-23382P |
| 英文名称 | ABCG1 Antibody Blocking Peptide |
| 中文名称 | 三磷酸腺苷结合盒亚家族G1封闭多肽 |
| 英文别名 | ABC transporter 8; Abc8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, sub family G WHITE member 1; homolog of Drosophila white; MGC34313; White protein homolog; White protein homolog ATP binding cassette transporter 8; ABC8; ABCG1; ABCG1_HUMAN; ATP-binding cassette sub family G member 1; WHT1; WHITE1; wht1. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cardiovascular > Atherosclerosis > Lipid transport Cardiovascular > Atherosclerosis > Lipoprotein metabolism Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipoprotein metabolism Metabolism > Types of disease > Cancer Metabolism > Types of disease > Heart disease Neuroscience > Cell Type Marker > Glia marker > Astrocyte marker Signal Transduction > Metabolism > Lipid metabolism |
| 亚基 | May form heterodimers with several heterologous partners of the ABCG subfamily. |
| 亚细胞定位 | Endoplasmic reticulum membrane. Golgi apparatus membrane. Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes. |
| 组织特异性 | Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease. |
| 翻译后修饰 | Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum. |
| 相似性 | Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. Contains 1 ABC transmembrane type-2 domain. Contains 1 ABC transporter domain. |
| 功能 | Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. |
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