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500ug/1mg
| 规格: | 500ug | 产品价格: | ¥880.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥1380.0 |
| 产品编号 | bs-0269P |
| 英文名称 | FOXP3 Antibody Blocking Peptide |
| 中文名称 | 叉头蛋白P3封闭多肽 |
| 英文别名 | Forkhead box protein P3; forkhead box P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; JM2; AIID; IPEX; PIDX; XPID; DIETER; FOXP3_HUMAN; |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Chromatid Cohesion Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXP Immunology > Adaptive Immunity > Regulatory T Cells |
| 亚基 | Interacts with IKZF3. |
| 亚细胞定位 | Nucleus (Potential). |
| 翻译后修饰 | Acetylation on lysine residues stabilizes FOXP3 and promotes differentiation of T-cells into induced regulatory T-cells (iTregs) associated with suppressive functions. Deacetylated by SIRT1. |
| 相似性 | Contains 1 C2H2-type zinc finger. Contains 1 fork-head DNA-binding domain. |
| 功能 | Probable transcription factor. Plays a critical role in the control of immune response. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]. |
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FOXP3 Antibody Blocking Peptide(bs-0269P)-500ug/1mg
¥880 - 1380







