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- Bioss
- bs-12353P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-12353P |
| 英文名称 | HES7 Antibody Blocking Peptide |
| 中文名称 | 转录因子HES7封闭多肽 |
| 英文别名 | bHLH factor Hes7; bHLHb37; Class B basic helix loop helix protein 37; Class B basic helix-loop-helix protein 37; hairy and enhancer of split 7; Hes7; HES7_HUMAN; hHes7; SCDO4; Transcription factor HES 7; Transcription factor HES-7. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Lineage specification > Mesoderm Epigenetics and Nuclear Signaling > Transcription > Other factors Stem Cells > Lineage Markers > Mesoderm |
| 亚基 | Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family (By similarity). |
| 亚细胞定位 | Nucleus. |
| 相似性 | Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 Orange domain. |
| 功能 | Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HES7 is a 225 amino acid transcriptional repressor protein. Localized to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one Orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterized by deformities of the chest and spine. |
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HES7 Antibody Blocking Peptide(bs-12353P)-500ug
￥880
