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- bs-23361P
- 2025年10月16日
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500ug
| 产品编号 | bs-23361P |
| 英文名称 | GCLM Antibody Blocking Peptide |
| 中文名称 | γ 谷氨酰半胱氨酸连接酶调节亚基封闭多肽 |
| 英文别名 | Glutamate-Cysteine Ligase Modifier Subunit; Gamma-Glutamylcysteine Synthetase Regulatory Subunit; Glutamate--Cysteine Ligase Modifier Subunit; Gamma-ECS Regulatory Subunit; GCS Light Chain; GLCLR; Glutamate-Cysteine Ligase (Gamma-Glutamylcysteine Synthetase), Regulatory (30.8kD); Glutamate-Cysteine Ligase Modifier Subunit Delta2 Alternative Splicing; Glutamate--Cysteine Ligase Regulatory Subunit; Glutamate-Cysteine Ligase Regulatory Protein; Glutamate-Cysteine Ligase, Modifier Subunit; Gamma-Glutamylcysteine Synthetase; GSC Light Chain; GSH0_HUMAN; |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Metabolism > Types of disease > Cancer Neuroscience > Neurotransmitter > Amino Acids > Glutamate Signal Transduction > Metabolism > Amino Acids Signal Transduction > Metabolism > Drug metabolism Signal Transduction > Metabolism > Energy Metabolism Signal Transduction > Metabolism > Mitochondrial |
| 亚基 | Heterodimer of a catalytic heavy chain and a regulatory light chain. |
| 亚细胞定位 | Cytosol |
| 组织特异性 | In all tissues examined. Highest levels in skeletal muscle. |
| 相似性 | Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily. |
| 功能 | This protein is involved in step 1 of the subpathway that synthesizes glutathione from L-cysteine and L-glutamate. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
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