- ￥880
- Bioss
- bs-17508P
- 2025年10月16日
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500ug
| 产品编号 | bs-17508P |
| 英文名称 | SKOR1 Antibody Blocking Peptide |
| 中文名称 | SKOR1蛋白封闭多肽 |
| 英文别名 | AV273001; C230094B15Rik; Corepressor for LBX1; CORL1; Functional smad suppressing element 15; Functional Smad suppressing element on chromosome 15; Functional Smad-suppressing element on chromosome 15; Fussel-15; FUSSEL15; Ladybird homeobox corepressor 1; Lbx1 corepressor 1; LBXCOR1; Lbxcor1 homolog; SKI family transcriptional corepressor 1; Skor1; SKOR1_HUMAN; Transcriptional corepressor CORL1. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Present specifically in cerebellar Purkinje cells (at protein level). |
| 相似性 | Belongs to the SKI family. |
| 功能 | Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | LBXCOR1 is a 965 amino acid protein belonging to the SKI family. Localizing to nucleus, LBXCOR1 is highly expressed in the central nervous system (CNS) as well as developing spinal cord and adult brain and testis. LBXCOR1 contains a CH1 domain which is required for transcriptional repression and also acts as a transcriptional co-repressor of LBX1. LBXCOR1 additionally interacts with SMAD1, SMAD2 and SMAD3, and inhibits BMP signaling. Existing as three alternatively spliced isoforms, the gene encoding LBXCOR1 maps to human chromosome 15q23. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and consists of about 3% of the human genome. Angelman and Prader-Willi syndromes, as well as Tay-Sachs disease and Marfan syndorme, are all associated with mutations to chromosome 15. |
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SKOR1 Antibody Blocking Peptide(bs-17508P)-500ug
￥880
