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skd Antibody Blocking Peptide(

bs-17512P)-500ug
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  • bs-17512P
  • 2025年10月16日
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      500ug

    产品编号bs-17512P
    英文名称skd Antibody Blocking Peptide
    中文名称Skuld蛋白封闭多肽
    英文别名CG9936-PC isoform C; Cg9936-pd isoform d; Jlkjlkj; MED13_DROME; Med13; Mediator complex subunit 13; Pap/DTRAP240; Protein blind spot; skd; Transcriptional coactivator blind spot; Trap240.
    纯化方法HPLC
    亚基Component of the Cdk8 module of the Mediator complex, composed of CycC, Cdk8, kto and skd.
    亚细胞定位Nuclear
    相似性Belongs to the Mediator complex subunit 13 family.
    功能Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development. Required for activated transcription of the MtnB and MtnD genes.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Sklud is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development.

     

     

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