- ￥880
- Bioss
- bs-17505P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17505P |
| 英文名称 | SIX5 Antibody Blocking Peptide |
| 中文名称 | 糖尿病相关同源结构域蛋白SIX5封闭多肽 |
| 英文别名 | BOR2; DM locus associated homeodomain protein; DM locus-associated homeodomain protein; DMAHP; Dystrophia myotonica associated homeodomain protein; Homeobox protein SIX5; Sine oculis homeobox homolog 5; sine oculis related homeobox 5 homolog (Drosophila); SIX homeobox 5; SIX5; SIX5_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Expressed in adult but not in fetal eyes. Found in corneal epithelium and endothelium, lens epithelium, ciliary body epithelia, cellular layers of the retina and the sclera. |
| 相似性 | Belongs to the SIX/Sine oculis homeobox family. Contains 1 homeobox DNA-binding domain. |
| 功能 | Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2. [provided by RefSeq, Jul 2009] |
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SIX5 Antibody Blocking Peptide(bs-17505P)-500ug
￥880
