SIL1 Antibody Blocking Peptide(bs-17493P)-500ug

SIL1 Antibody Blocking Peptide

(bs-17493P)-500ug
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  • ¥880
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  • bs-17493P
  • 2025年10月16日
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      500ug

    产品编号bs-17493P
    英文名称SIL1 Antibody Blocking Peptide
    中文名称内质网分子伴侣SIL1封闭多肽
    英文别名BAP; BiP associated protein; BiP-associated protein; Endoplasmic reticulum chaperone SIL 1; Endoplasmic reticulum chaperone SIL1; MSS; Nucleotide exchange factor SIL 1; Nucleotide exchange factor SIL1; SIL 1; sil1; SIL1 homolog; SIL1 homolog endoplasmic reticulum chaperone (S. cerevisiae); SIL1 homolog endoplasmic reticulum chaperone; SIL1_HUMAN; UGL 5; ULG5.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins

    Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

    Signal Transduction > Protein Trafficking > ER Proteins

    亚细胞定位Endoplasmic reticulum lumen.
    组织特异性Highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. Also expressed in colon, heart, lung, ovary, pancreas, peripheral leukocyte, prostate, spleen and thymus. Expressed at low levels throughout the brain.
    翻译后修饰N-glycosylated.
    相似性Belongs to the SIL1 family.
    功能Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]

     

     

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