AHNAK Antibody Blocking Peptide(bs-13624P)-500ug

AHNAK Antibody Blocking Peptid

e(bs-13624P)-500ug
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  • ¥880
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  • bs-13624P
  • 2025年10月16日
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      500ug

    产品编号bs-13624P
    英文名称AHNAK Antibody Blocking Peptide
    中文名称神经细胞分化相关蛋白AHNAK封闭多肽
    英文别名AHNAK; AHNAK nucleoprotein (desmoyokin); AHNAKRS; AHNK_HUMAN; Desmoyokin; Fragments; MGC5395; Neuroblast differentiation associated protein AHNAK; Neuroblast differentiation-associated protein AHNAK; PM227.
    纯化方法HPLC
    研究领域

    Cancer > Tumor biomarkers

    Signal Transduction > Adapters > Cytoplasmic

    Signal Transduction > Adapters > Transmembrane

    亚基Interacts with DYSF; the interaction is direct and Ca(2+)-independent.
    亚细胞定位Nucleus.
    相似性Contains 1 PDZ (DHR) domain.
    功能May be required for neuronal cell differentiation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料AHNAK is a 5,890 amino acid protein encoded by the human gene AHNAK. The intronless AHNAK gene is located on human chromosome 11q12 and has three main structural regions: the 251 amino acid N-terminus, a large central region of 4390 amino acids with multiple repeated units of about 128 amino acids in length, and the 1002 amino acid C-terminus. The central region seems to have antiparallel beta-strands connected by intervening loops. Several putative regulatory elements are clustered within the C-terminal region, including nuclear export localization signals, a leucine zipper, and potential phosphorylation sites for Akt1 and PKC. AHNAK is believed to be an important signalling molecule involved in a wide range of physiological activities and may be required for neuronal cell differentiation.. AHNAK also appears to influence b-adrenergic regulation of cardiac L-type Ca2+ channel function.

     

     

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