CEP57 Antibody Blocking Peptide(bs-13608P)-500ug

CEP57 Antibody Blocking Peptid

e(bs-13608P)-500ug
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  • bs-13608P
  • 2025年10月16日
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      500ug

    产品编号bs-13608P
    英文名称CEP57 Antibody Blocking Peptide
    中文名称睾丸特异性蛋白57封闭多肽
    英文别名Centrosomal protein 57kDa; Centrosomal protein of 57 kDa; Cep57; Cep57 protein; CEP57_HUMAN; FGF2 interacting protein; FGF2-interacting protein; KIAA0092; MVA2; PIG8; Proliferation inducing protein 8; Testis specific protein 57; Testis-specific protein 57; Translokin; TSP57.
    纯化方法HPLC
    研究领域

    Signal Transduction > Growth Factors/Hormones > FGF

    Signal Transduction > Protein Trafficking > Nuclear Import / Export

    Stem Cells > Germline Stem Cells > Spermatogonial Stem Cells

    亚细胞定位Nucleus. Cytoplasm.
    组织特异性Ubiquitous.
    相似性Belongs to the translokin family.
    功能Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CEP57 (centrosomal protein 57kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88% sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.

     

     

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