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- Bioss
- bs-13606P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13606P |
| 英文名称 | BCL6B Antibody Blocking Peptide |
| 中文名称 | BCL6B封闭多肽 |
| 英文别名 | B cell CLL/lymphoma 6, member B (zinc finger protein); B-cell CLL/lymphoma 6, member B (zinc finger protein); BAZF; Bcl6 associated zinc finger protein; Bcl6-associated zinc finger protein; ZBTB28; Zinc finger protein 62; ZNF62; BCL6B_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Stem Cells > Germline Stem Cells > Spermatogonial Stem Cells |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Ubiquitously expressed with higher expression found in heart and placenta. |
| 相似性 | Contains 1 BTB (POZ) domain. Contains 5 C2H2-type zinc fingers. |
| 功能 | BCL6B acts as a sequence-specific transcriptional repressor in association with BCL6. It may function in a narrow stage or be related to some events in the early B-cell development. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFⅹB expression, thereby inhibiting NFⅹB-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. |
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BCL6B Antibody Blocking Peptide(bs-13606P)-500ug
￥880
